In 1993, the Our Lady of the Angels Seminary opened up M. A. courses in Pastoral Ministry and in Theology, of which the Department of Education Culture and Sports officially granted respective Government Recognitions on April 15, 1993. On the one hand, the M. A. in Pastoral Ministry became the M. A. Program of Our Lady of the Angels Seminary – Inter-Congregational Theological Center (OLAS – ICTC). The M. A. in Theology, on the other hand, became the M. A. Program of Our Lady of the Angels Seminary – Franciscan School of Theology (OLAS – FST). In the 1990s, several dioceses began to send their candidates to study at OLAS.
In the Academic Year 2010-2011, the Our Lady of the Angels Seminary opened up for the lay student-catechists of the Roman Catholic Diocese of Novaliches through its Council of the Laity of Novaliches (CLAN), offering them A. B. Theology in view of eventually establishing education-related courses. There is an ongoing initiative on the part of the Our Lady of the Angels Seminary–College to expand in terms of programs to continue to cater to the needs of the training and education of catechists of the nearby dioceses.
In the Academic Year 2010-2011, St. Francis School–Quezon City, through the assistance of St. Francis School–Sta. Ana, began to offer programs for Nursery and Kinder within the compound of the Our Lady of the Angels Seminary. The following Academic Year 2011-2012, St. Francis School–Quezon City started offering program for Grade I. Then St. Francis School–Quezon City began offering Grades II, III, IV, V and VI for the succeeding Academic Years. There was a groundbreaking of the K to 12 Building on October 7, 2016. At present there is an ongoing process to have St. Francis School–Quezon City be integrated to the OLAS–College.
In 2012 the Our Lady of the Angels celebrated the 50th Year of its foundation. With new vigor, it aimed to expand in terms of its educational programs in order to respond with relevance to the challenges of the Philippine society. In 2013, the R. A. 10533 or the K to 12 Law was enacted. In 2015, the ASEAN nations began the ASEAN Integration. These two important events, which are now changing the Philippine educational landscape, became part of the impetus that is now moving the Our Lady of the Angels Seminary, as an educational institution, to transform itself into a self-sustaining academic institution.
On July 28, 2015, the Securities and Exchange Commission of the Republic of the Philippines granted the certification to Our Lady of the Angles Seminary, through its newly amended Articles of Incorporation and By-Laws (amended on February 14, 2015), under the legal name OUR LADY OF THE ANGELS SEMINARY–COLLEGE (Formerly: SUPERIOR OF THE FRANCISCAN FILIPINO SEMINARY, INC.).
Responding to the mandate of the East Asia Conference of the OFM in Asia with the end-view of fostering English as the common language within the East Asian region, the Our Lady of the Angels Seminary–College began to offer summer English Program (English as Second Language/ ESL) in 2016 in order to cater to the needs of Asian friars who want to learn the English Language.